Publications

共著論文

2023

  • Aoyagi, R., Maehara, T., Koga, R., Munemura, R., Tomonaga, T., Murakami, Y., Doi, A., Yamamoto, H., Kiyoshima, T., Kawano, S., & Nakamura, S. (2023). Single-cell transcriptomics reveals granzyme K-expressing cytotoxic Tfh cells in tertiary lymphoid structures in IgG4-RD. The Journal of Allergy and Clinical Immunology. https://doi.org/10.1016/j.jaci.2023.08.019

2022

  • Munemura, R., Maehara, T., Murakami, Y., Koga, R., Aoyagi, R., Kaneko, N., Doi, A., Perugino, C. A., Della-Torre, E., Saeki, T., Sato, Y., Yamamoto, H., Kiyoshima, T., Stone, J. H., Pillai, S., & Nakamura, S. (2022). Distinct disease-specific Tfh cell populations in 2 different fibrotic diseases: IgG4-related disease and Kimura disease. Journal of Allergy and Clinical Immunology, 150(2), 440-455.e17. https://doi.org/10.1016/j.jaci.2022.03.034

2021

  • Nogami, M., Ishikawa, M., Doi, A., Sano, O., Sone, T., Akiyama, T., … Okano, H. (2021). Identification of hub molecules of FUS-ALS by Bayesian gene regulatory network analysis of iPSC model: iBRN. Neurobiology of Disease, 155. https://doi.org/10.1016/j.nbd.2021.105364

2019

  • Ozuru R, Wakao S, Tsuji T, et al. Rescue from Stx2-Producing E. coli-Associated Encephalopathy by Intravenous Injection of Muse Cells in NOD-SCID Mice. Mol Ther. 2019. doi:10.1016/j.ymthe.2019.09.023

2017

  • Tsuru, M., Sata, M., Tanaka, M., Umeyama, H., Kodera, Y., Shiwa, M., … Nagata, K. (2017). Retrospective Proteomic Analysis of a Novel, Cancer Metastasis-Promoting RGD-Containing Peptide. Translational Oncology, 10(6), 998–1007. https://doi.org/10.1016/j.tranon.2017.10.001

2016

  • Matsunaga, N., Ikeda, E., Kakimoto, K., Watanabe, M., Shindo, N., Tsuruta, A., … Ohdo, S. (2016). Inhibition of G0/G1 Switch 2 Ameliorates Renal Inflammation in Chronic Kidney Disease. EBioMedicine, 13, 1–12. http://doi.org/10.1016/j.ebiom.2016.10.008
  • Hamamura, K., Matsunaga, N., Ikeda, E., Kondo, H., Ikeyama, H., Tokushige, K., … Ohdo, S. (2016). Alterations of hepatic metabolism in chronic kidney disease via D-box-binding protein aggravate the renal dysfunction. Journal of Biological Chemistry, 291(10), 4913–4927. http://doi.org/10.1074/jbc.M115.696930
  • Arakawa, F., Kimura, Y., Yoshida, N., Miyoshi, H., Doi, A., Yasuda, K., … Ohshima, K. (2016). Identification of miR-15b as a transformation-related factor in mantle cell lymphoma. International Journal of Oncology, 48(2), 485–492. https://doi.org/10.3892/ijo.2015.3295
  • Sugiyama, D., Joshi, A., Kulkeaw, K., Tan, K. sinn, Yokoo-Inoue, T., Mizuochi-Yanagi, C., … Forrest, A. R. R. (2016). A Transcriptional switch point during hematopoietic stem and progenitor cell ontogeny. Stem Cells and Development, 26(5), scd.2016.0194. https://doi.org/10.1089/scd.2016.0194

2015

  • Kinjyo, I., Qin, J., Tan, S.-Y., Wellard, C. J., Mrass, P., Ritchie, W., … Weninger, W. (2015). Real-time tracking of cell cycle progression during CD8+ effector and memory T-cell differentiation. Nature Communications, 6(May 2014), 6301. http://doi.org/10.1038/ncomms7301
  • Fujimoto, K., Fujii, G., Taguchi, K., Yasuda, K., Matsuo, Y., Hashiyama, A., … Wada, M. (2015). Involvement of trefoil factor family 2 in the enlargement of intestinal tumors in ApcMin/+ mice. Biochemical and Biophysical Research Communications, 463(4), 859–863. http://doi.org/10.1016/j.bbrc.2015.06.025

2014

  • Miyahara, E., Nishikawa, T., Takeuchi, T., Yasuda, K., Okamoto, Y., Kawano, Y., & Horiuchi, M. (2014). Effect of myeloperoxidase inhibition on gene expression profiles in HL-60 cells exposed to 1,2,4,-benzenetriol. Toxicology, 317, 50–57.

2013

  • Kimura, Y., Arakawa, F., Kiyasu, J., Miyoshi, H., Yoshida, M., Ichikawa, A., et al. (2013). The Wnt signaling pathway and mitotic regulators in the initiation and evolution of mantle cell lymphoma: Gene expression analysis. International journal of oncology, 43(2), 457–468. doi:10.3892/ijo.2013.1982

2012

  • Koide, N., Yasuda, K., Kadomatsu, K., & Takei, Y. (2012). Establishment and optimal culture conditions of microrna-induced pluripotent stem cells generated from HEK293 cells via transfection of microrna-302s expression vector. Nagoya Journal of Medical Science, 74(1-2), 157–65.
  • Yoshida, S., Arakawa, F., Higuchi, F., Ishibashi, Y., Goto, M., Sugita, Y., Nomura, Y., et al. (2012). Gene expression analysis of rheumatoid arthritis synovial lining regions by cDNA microarray combined with laser microdissection: up-regulation of inflammation-associated STAT1, IRF1, CXCL9, CXCL10, and CCL5. Scandinavian journal of rheumatology, 41(3), 170–179. doi:10.3109/03009742.2011.623137

2011

  • Hurley, D., Araki, H., Tamada, Y., Dunmore, B., Sanders, D., Humphreys, S., Affara, M., et al. (2011). Gene network inference and visualization tools for biologists: application to new human transcriptome datasets Nucleic Acids Research. doi:10.1093/nar/gkr902.
  • Komatsu, N., Matsueda, S., Tashiro, K., Ioji, T., Shichijo, S., Noguchi, M., Yamada, A., et al. (2011). Gene expression profiles in peripheral blood as a biomarker in cancer patients receiving peptide vaccination. Cancer. doi:10.1002/cncr.26636

2010

  • Nakamura, A., Ueno, T., Yagi, Y., Okuda, K., Ogata, T., Nakamura, T., Torimura, T., et al. (2010). Human primary cultured hepatic stellate cells can be cryopreserved. Medical molecular morphology, 43(2), 107–115. doi:10.1007/s00795-009-0484-5.

2009

  • Araki, H., Tamada, Y., Imoto, S., Dunmore, B., Sanders, D., Humphrey, S., Nagasaki, M., et al. (2009). Analysis of PPARalpha-dependent and PPARalpha-independent transcript regulation following fenofibrate treatment of human endothelial cells. Angiogenesis, 12(3), 221–229. doi:10.1007/s10456-009-9142-8.

Supported Works

2023

  • Hayashi, Y., Kimura, S., Yano, E., Yoshimoto, S., Saeki, A., Yasukochi, A., Hatakeyama, Y., Moriyama, M., Nakamura, S., Jimi, E., & Kawakubo-Yasukochi, T. (2023). Id4 modulates salivary gland homeostasis and its expression is downregulated in IgG4-related disease via miR-486-5p. Biochimica et Biophysica Acta (BBA) – Molecular Cell Research, 1870(2), 119404. https://doi.org/10.1016/j.bbamcr.2022.119404
  • Otsuji, R., Fujioka, Y., Hata, N., Kuga, D., Sangatsuda, Y., Takigawa, K., Funakoshi, Y., Sako, A., Yamamoto, H., Nakamizo, A., Mizoguchi, M., & Yoshimoto, K. (2023). Liquid biopsy with multiplex ligation-dependent probe amplification targeting cell-free tumor DNA in cerebrospinal fluid from patients with adult diffuse glioma. Neuro-Oncology Advances, 5(1). https://doi.org/10.1093/noajnl/vdac178
  • Suzuki, H., Iwamoto, H., Seki, T., Nakamura, T., Masuda, A., Sakaue, T., Tanaka, T., Imamura, Y., Niizeki, T., Nakano, M., Shimose, S., Shirono, T., Noda, Y., Kamachi, N., Sakai, M., Morita, K., Nakayama, M., Yoshizumi, T., Kuromatsu, R., … Torimura, T. (2023). Tumor-derived insulin-like growth factor-binding protein-1 contributes to resistance of hepatocellular carcinoma to tyrosine kinase inhibitors. Cancer Communications (London, England), 43(4), 415–434. https://doi.org/10.1002/cac2.12411
  • Inada, A., Yasunami, Y., Yoshiki, A., Nabeshima, Y.-I., & Inada, O. (2023). Greb1 Transiently Accelerates Pancreatic β-Cell Proliferation in Diabetic Mice Exposed to Estradiol. The American Journal of Pathology, 193(8), 1081–1100. https://doi.org/10.1016/j.ajpath.2023.04.012
  • Sakata, N., Yoshimatsu, G., Kawakami, R., Aoyagi, C., & Kodama, S. (2023). Optimal temperature for the long-term culture of adult porcine islets for xenotransplantation. Frontiers in Immunology, 14, 1280668. https://doi.org/10.3389/fimmu.2023.1280668
  • Hirayama, A., Tanaka, K., Tsutsumi, H., Nakanishi, T., Yamashita, S., Mizusaki, S., Ishii, Y., Ota, K., Yoneshima, Y., Iwama, E., & Okamoto, I. (2023). Regulation of PD-L1 expression in non-small cell lung cancer by interleukin-1β. Frontiers in Immunology, 14, 1192861. https://doi.org/10.3389/fimmu.2023.1192861

2022

  • Yokoyama, K., Mitoma, H., Kawano, S., Yamauchi, Y., Wang, Q., Ayano, M., Kimoto, Y., Ono, N., Arinobu, Y., Akashi, K., Horiuchi, T., & Niiro, H. (2022). CEACAM 1, 3, 5 and 6 -positive classical monocytes correlate with interstitial lung disease in early systemic sclerosis. Frontiers in Immunology, 13. https://doi.org/10.3389/fimmu.2022.1016914
  • Hatano, S., Mine, K., Noguchi, N., Matsumoto, M., Baba, Y., & Yoshikai, Y. (2022). MHC class II inhibits the generation of IL‐17A + Vγ6 γδ T cells in the thymus at perinatal stage. European Journal of Immunology, 52(8), 1366–1368. https://doi.org/10.1002/eji.202149542
  • Kanemura, H., Hayashi, H., Tomida, S., Tanizaki, J., Suzuki, S., Kawanaka, Y., Tsuya, A., Fukuda, Y., Kaneda, H., Kudo, K., Takahama, T., Imai, R., Haratani, K., Chiba, Y., Otani, T., Ito, A., Sakai, K., Nishio, K., & Nakagawa, K. (2022). The Tumor Immune Microenvironment and Frameshift Neoantigen Load Determine Response to PD-L1 Blockade in Extensive-Stage SCLC. JTO Clinical and Research Reports, 3(8), 100373. https://doi.org/10.1016/j.jtocrr.2022.100373
  • Miyata, N., Ito, T., Nakashima, M., Fujii, S., & Kuge, O. (2022). Mitochondrial phosphatidylethanolamine synthesis affects mitochondrial energy metabolism and quiescence entry through attenuation of Snf1/AMPK signaling in yeast. The FASEB Journal, 36(7). https://doi.org/10.1096/fj.202101600RR
  • Shinkawa, T., Ohuchida, K., Mochida, Y., Sakihama, K., Iwamoto, C., Abe, T., Ideno, N., Mizuuchi, Y., Shindo, K., Ikenaga, N., Moriyama, T., Nakata, K., Oda, Y., & Nakamura, M. (2022). Subtypes in pancreatic ductal adenocarcinoma based on niche factor dependency show distinct drug treatment responses. Journal of Experimental & Clinical Cancer Research, 41(1), 89. https://doi.org/10.1186/s13046-022-02301-9
  • Otsuka, H., Yokomizo, H., Nakamura, S., Izumi, Y., Takahashi, M., Obara, S., Nakao, M., Ikeda, Y., Sato, N., Sakamoto, R., Miyachi, Y., Miyazawa, T., Bamba, T., & Ogawa, Y. (2022). Differential effect of canagliflozin, a sodium–glucose cotransporter 2 (SGLT2) inhibitor, on slow and fast skeletal muscles from nondiabetic mice. Biochemical Journal, 479(3), 425–444. https://doi.org/10.1042/BCJ20210700

2021

  • Miyamoto, S., Yoshikawa, H., & Nakata, K. (2021). Axial mechanical loading to ex vivo mouse long bone regulates endochondral ossification and endosteal mineralization through activation of the BMP-Smad pathway during postnatal growth. Bone Reports, 15. https://doi.org/10.1016/j.bonr.2021.101088
  • Hamura, R., Shirai, Y., Shimada, Y., Saito, N., Taniai, T., Horiuchi, T., … Yanaga, K. (2021). Suppression of lysosomal acid alpha-glucosidase impacts the modulation of transcription factor EB translocation in pancreatic cancer. Cancer Science. https://doi.org/10.1111/cas.14921
  • Hashida, R., Matsuse, H., Kawaguchi, T., Yoshio, S., Bekki, M., Iwanaga, S., … Shiba, N. (2021). Effects of A Low‐Intensity Resistance Exercise Program on Serum miR‐630, miR‐5703, and Fractalkine/CX3CL1 Expressions in Subjects with No Exercise Habits: A Preliminary Study. Hepatology Research, (May), 1–11. https://doi.org/10.1111/hepr.13670
  • Kiyozawa, D., Kohashi, K., Takamatsu, D., Yamamoto, T., Eto, M., Iwasaki, T., … Oda, Y. (2021). Morphological, immunohistochemical, and genomic analyses of papillary renal neoplasm with reverse polarity. Human Pathology, 112. https://doi.org/10.1016/j.humpath.2021.03.009
  • Hasegawa, K., Fujii, S., Matsumoto, S., Tajiri, Y., Kikuchi, A., & Kiyoshima, T. (2021). YAP signaling induces PIEZO1 to promote oral squamous cell carcinoma cell proliferation. Journal of Pathology, 253(1). https://doi.org/10.1002/path.5553
  • Asai, M., Koike, Y., Kuwatsuka, Y., Yagi, Y., Kashiyama, K., Tanaka, K., Mishima, H., Yoshiura, K., Utani, A., & Murota, H. (2021). Multifaceted array-based keloidal gene expression profiling reveals specific MDFI upregulation in keloid lesions. Clinical and Experimental Dermatology, 46(7), 1255–1261. https://doi.org/10.1111/ced.14698
  • Tajiri, R., Shiba, E., Iwamura, R., Kubo, C., Nawata, A., Harada, H., Yoshino, K., & Hisaoka, M. (2021). Potential pathogenetic link between angiomyofibroblastoma and superficial myofibroblastoma in the female lower genital tract based on a novel MTG1-CYP2E1 fusion. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc, 34(12), 2222–2228. https://doi.org/10.1038/s41379-021-00886-8
  • Kawakubo-Yasukochi, T., Yano, E., Kimura, S., Nishinakagawa, T., Mizokami, A., Hayashi, Y., Hatakeyama, Y., Ohe, K., Yasukochi, A., Nakamura, S., Jimi, E., & Hirata, M. (2021). Hepatic glycogenolysis is determined by maternal high-calorie diet via methylation of Pygl and it is modified by oteocalcin administration in mice. Molecular Metabolism, 54, 101360. https://doi.org/10.1016/j.molmet.2021.101360

2020

  • Wang, Q., Ishizawa, K., Li, J., Fujii, W., Nemoto, Y., Yamazaki, O., … Shibata, S. (2020). Urinary phosphate-containing nanoparticle contributes to inflammation and kidney injury in a salt-sensitive hypertension rat model. Communications Biology, 3(1). https://doi.org/10.1038/s42003-020-01298-1
  • Yasukawa K, Kinoshita D, Yaku K, Nakagawa T, Koshiba T. The microRNAs miR-302b and miR-372 regulate mitochondrial metabolism via the SLC25A12 transporter, which controls MAVS-mediated antiviral innate immunity. J Biol Chem. 2020;295(2):444-457. doi:10.1074/jbc.RA119.010511

2019

  • Kanaya HJ, Kobayakawa Y, Itoh TQ. Hydra vulgaris exhibits day-night variation in behavior and gene expression levels. Zool Lett. 2019. doi:10.1186/s40851-019-0127-1
  • Yoshimoto S, Tanaka F, Morita H, Hiraki A, Hashimoto S. Hypoxia-induced HIF-1α and ZEB1 are critical for the malignant transformation of ameloblastoma via TGF-β-dependent EMT. Cancer Med. 2019. doi:10.1002/cam4.2667

2018

  • Higa T, Takahashi H, Higa-Nakamine S, Suzuki M, Yamamoto H. Up-regulation of DUSP5 and DUSP6 by gonadotropin-releasing hormone in cultured hypothalamic neurons, GT1-7cells. Biomed Res. 2018. doi:10.2220/biomedres.39.149
  • Saga K, Iwashita Y, Hidano S, et al. Secondary Unconjugated Bile Acids Induce Hepatic Stellate Cell Activation. Int J Mol Sci. 2018. doi:10.3390/ijms19103043
  • Susa T, Iizuka M, Okinaga H, Tamamori-Adachi M, Okazaki T. Without 1α-hydroxylation, the gene expression profile of 25(OH)D3 treatment overlaps deeply with that of 1,25(OH)2D3 in prostate cancer cells. Sci Rep. 2018. doi:10.1038/s41598-018-27441-x
  • Kawakubo-Yasukochi, T., Morioka, M., Hazekawa, M., Yasukochi, A., Nishinakagawa, T., Ono, K., … Nakashima, M. (2018). miR-200c-3p spreads invasive capacity in human oral squamous cell carcinoma microenvironment. Molecular Carcinogenesis, 57(2), 295–302. http://doi.org/10.1002/mc.22744
  • Izumi, S., Higa-Nakamine, S., Nishi, H., Torihara, H., Uehara, A., Sugahara, K., … Yamamoto, H. (2018). Phosphorylation of epidermal growth factor receptor at serine 1047 in cultured lung alveolar epithelial cells by bradykinin B2 receptor stimulation. Pulmonary Pharmacology and Therapeutics, 48, 53–61. http://doi.org/10.1016/j.pupt.2017.09.002

2017

  • Hatano S, Murakami T, Noguchi N, Yamada H, Yoshikai Y. CD5−NK1.1+ γδ T Cells that Develop in a Bcl11b-Independent Manner Participate in Early Protection against Infection. Cell Rep. 2017. doi:10.1016/j.celrep.2017.10.007
  • Takikawa, T., Masamune, A., Yoshida, N., Hamada, S., Kogure, T., & Shimosegawa, T. (2016). Exosomes Derived From Pancreatic Stellate Cells. Pancreas, 0(0), 1. http://doi.org/10.1097/MPA.0000000000000722
  • Yoshida, N., Masamune, A., Hamada, S., Kikuta, K., Takikawa, T., Motoi, F., … Shimosegawa, T. (2017). Kindlin-2 in pancreatic stellate cells promotes the progression of pancreatic cancer. Cancer Letters, 390, 103–114. http://doi.org/10.1016/j.canlet.2017.01.008
  • Itoh, T., Nishinakamura, H., Kumano, K., Takahashi, H., & Kodama, S. (2017). The spleen is an ideal site for inducing transplanted islet graft expansion in mice. PLoS ONE, 12(1). https://doi.org/10.1371/journal.pone.0170899
  • Miura, S., & Suzuki, A. (2017). Generation of Mouse and Human Organoid-Forming Intestinal Progenitor Cells by Direct Lineage Reprogramming. Cell Stem Cell, 21(4), 456–471.e5. https://doi.org/10.1016/j.stem.2017.08.020

2016

  • Ohta, M., Moriyama, M., Maehara, T., Gion, Y., Furukawa, S., Tanaka, A., … Nakamura, S. (2016). DNA Microarray Analysis of Submandibular Glands in IgG4-Related Disease Indicates a Role for MARCO and Other Innate Immune-Related Proteins. Medicine, 95(7), e2853. http://doi.org/10.1097/MD.0000000000002853

2015

  • Ohkubo, K. et al. Moyamoya disease susceptibility gene RNF213 links inflammatory and angiogenic signals in endothelial cells. Sci. Rep. 5, 13191; doi: 10.1038/srep13191 (2015).
  • Kadooka, K., Fujii, K., Matsumoto, T., Sato, M., Morimatsu, F., Tashiro, K., … Katakura, Y. (2015). Mechanisms and consequences of carnosine-induced activation of intestinal epithelial cells. Journal of Functional Foods, 13, 32–37.

2013

  • Tsuru, M., Soejima, T., Shiba, N., Kimura, K., Sato, K., Toyama, Y., Nagata, K. (2013). PRELP Converts Stem Cells to Ligament Tissue and Zn(II) Influences Its Nuclear Expression. Stem Cells Dev., 2013 Feb 26.

2011

  • Nagata, M., Nakayama, H., Tanaka, T., Yoshida, R., Yoshitake, Y., Fukuma, D., Kawahara, K., et al. (2011). Overexpression of cIAP2 contributes to 5-FU resistance and a poor prognosis in oral squamous cell carcinoma. British journal of cancer. doi:10.1038/bjc.2011.387.
  • Sekiya, S., & Suzuki, A. (2011). Direct conversion of mouse fibroblasts to hepatocyte-like cells by defined factors. Nature, 475(7356), 390–393. doi:10.1007/s00795-009-0484-5.